Pathogenicity of a human thyroglobulin peptide (2340–2359) in mice with high or low genetic susceptibility to thyroiditis

We have previously identified a 20-mer peptide of human thyroglobulin (hTg), p2340 (aa2340–2359), which induced experimental autoimmune thyroiditis (EAT) in AKR/J (H-2(k)) and HLA-DR3 transgenic mice. In this study, we investigated the thyroiditogenic potential of p2340 in ‘high responder’ CBA/J (H-...

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Detalhes bibliográficos
Main Authors: Hatzioannou, Aikaterini, Liakata, Elisavet, Karras, Evangelos, Thrasyvoulides, Apollon, Alevizaki, Maria, Lymberi, Peggy
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266013/
https://ncbi.nlm.nih.gov/pubmed/17608692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02645.x
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