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A novel pathogenic peptide of thyroglobulin (2208–2227) induces autoreactive T-cell and B-cell responses in both high and low responder mouse strains
Experimental autoimmune thyroiditis (EAT) is commonly induced by thyroglobulin (Tg) or Tg peptides in mice genetically susceptible to thyroiditis. In the present study, we investigated the immunogenic and pathogenic potential of a novel 20mer human Tg peptide, p2208 (amino acids 2208–2227), in mouse...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley & Sons Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4008237/ https://ncbi.nlm.nih.gov/pubmed/24758369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12254 |
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