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Purification, crystallization and preliminary X-ray diffraction analysis of the Fyn SH2 domain and its complex with a phosphotyrosine peptide

SH2 domains are widespread protein-binding modules that recognize phosphotyrosines and play central roles in intracellular signalling pathways. The SH2 domain of the human protein tyrosine kinase Fyn has been expressed, purified and crystallized in the unbound state and in complex with a high-affini...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huculeci, Radu, Buts, Lieven, Lenaerts, Tom, van Nuland, Nico A. J., Garcia-Pino, Abel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310552/
https://ncbi.nlm.nih.gov/pubmed/22442244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112004186
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