Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing

Mint adaptor proteins bind to the amyloid precursor protein (APP) and regulate APP processing associated with Alzheimer’s disease; however, the molecular mechanisms underlying Mint regulation in APP binding and processing remain unclear. Biochemical, biophysical, and cellular experiments now show th...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Matos, Maria F., Xu, Yibin, Dulubova, Irina, Otwinowski, Zbyszek, Richardson, John M., Tomchick, Diana R., Rizo, Josep, Ho, Angela
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309763/
https://ncbi.nlm.nih.gov/pubmed/22355143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119075109
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla