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Recruitment of the Mint3 Adaptor Is Necessary for Export of the Amyloid Precursor Protein (APP) from the Golgi Complex

The amyloid precursor protein (APP) is a ubiquitously expressed single-pass transmembrane protein that undergoes proteolytic processing by secretases to generate the pathogenic amyloid-β peptide, the major component in Alzheimer plaques. The traffic of APP through the cell determines its exposure to...

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Bibliografske podrobnosti
Main Authors: Caster, Amanda H., Kahn, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789957/
https://ncbi.nlm.nih.gov/pubmed/23965993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.481101
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