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Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
BACKGROUND: Cyclin-dependent kinases (CDKs) regulate cell proliferation and coordinate the cell cycle checkpoint response to DNA damage. Although inhibitors with varying selectivity to specific CDK family members have been developed, selective CDK4/6 inhibitors have emerged as the most attractive an...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309128/ https://ncbi.nlm.nih.gov/pubmed/22302033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs002 |
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