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Refined homology model of monoacylglycerol lipase: Toward a selective inhibitor
Monoacylglycerol lipase (MGL) is primarily responsible for the hydrolysis of 2-arachidonoylglycerol (2-AG), an endocannabinoid with full agonist activity at both cannabinoid receptors. Increased tissue 2-AG levels consequent to MGL inhibition are considered therapeutic against pain, inflammation, an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308346/ https://ncbi.nlm.nih.gov/pubmed/19543978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-009-9289-9 |
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