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Highly predictive ligand-based pharmacophore and homology models of ABHD6

α/β-hydrolase domain-containing 6 (ABHD6) represents a potentially attractive therapeutic target for indirectly potentiating 2-arachidonoylglycerol signaling, however, the enzyme is currently largely uncharacterized. Here we describe a five element, ligand-based pharmacophore model along with a refi...

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Autori principali: Bowman, Anna L., Makriyannis, Alexandros
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573238/
https://ncbi.nlm.nih.gov/pubmed/23110439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12086
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