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Synthesis and characterization of 2-substituted bornane pharmacophores for novel cannabinergic ligands

Analogously to the fenchyl and adamantyl groups, the bornyl and epimeric isobornyl groups are compact lipophilic substituents that can be incorporated into drug design to improve pharmacological or physicochemical properties. Methods are reported for the synthesis and characterization of 2-substitut...

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Detalhes bibliográficos
Main Authors: Duclos, Richard I., Lu, Dai, Guo, Jianxin, Makriyannis, Alexandros
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738215/
https://ncbi.nlm.nih.gov/pubmed/23935221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.07.029
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