C-Ring Cannabinoid Lactones: A Novel Cannabinergic Chemotype

[Image: see text] As a part of our controlled-deactivation ligand development project, we recently disclosed a series of (−)-Δ(8)-tetrahydrocannabinols (THCs) with a metabolically labile ester group at the 2′-position of the side chain. Now, we have replaced the C-ring in the classical THC structure...

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Autors principals: Sharma, Rishi, Nikas, Spyros P., Guo, Jason Jianxin, Mallipeddi, Srikrishnan, Wood, JodiAnne T., Makriyannis, Alexandros
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027620/
https://ncbi.nlm.nih.gov/pubmed/24900848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4005304
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