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Defining the Herpes Simplex Virus-Specific CD8(+) T Cell Repertoire in C57BL/6 Mice

HSV type 1 (HSV-1) expresses its genes sequentially as immediate early (α), early (β), leaky late (γ1), and true late (γ2), where viral DNA synthesis is an absolute prerequisite only for γ2 gene expression. The γ1 protein glycoprotein B (gB) contains a strongly immunodominant CD8(+) T cell epitope (...

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Detalhes bibliográficos
Main Authors: St. Leger, Anthony J., Peters, Bjoern, Sidney, John, Sette, Alessandro, Hendricks, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308013/
https://ncbi.nlm.nih.gov/pubmed/21357536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003735
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