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Defining the Herpes Simplex Virus-Specific CD8(+) T Cell Repertoire in C57BL/6 Mice
HSV type 1 (HSV-1) expresses its genes sequentially as immediate early (α), early (β), leaky late (γ1), and true late (γ2), where viral DNA synthesis is an absolute prerequisite only for γ2 gene expression. The γ1 protein glycoprotein B (gB) contains a strongly immunodominant CD8(+) T cell epitope (...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308013/ https://ncbi.nlm.nih.gov/pubmed/21357536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003735 |
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