Terminally differentiated astrocytes lack DNA damage response signaling and are radioresistant but retain DNA repair proficiency

The impact and consequences of damage generation into genomic DNA, especially in the form of DNA double-strand breaks, and of the DNA-damage response (DDR) pathways that are promptly activated, have been elucidated in great detail. Most of this research, however, has been performed on proliferating,...

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Bibliographic Details
Main Authors: Schneider, L, Fumagalli, M, d'Adda di Fagagna, F
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307974/
https://ncbi.nlm.nih.gov/pubmed/21979466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.129
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