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Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans

The germline of Caenorhabditis elegans is a well-established model for DNA damage response (DDR) studies. However, the molecular basis of the observed cell death resistance in the soma of these animals remains unknown. We established a set of techniques to study ionizing radiation-induced DNA damage...

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Détails bibliographiques
Auteurs principaux: Vermezovic, J, Stergiou, L, Hengartner, M O, d'Adda di Fagagna, F
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469062/
https://ncbi.nlm.nih.gov/pubmed/22705849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.69
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