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Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation
Bromodeoxyuridine (5-bromo-2′-deoxyuridine, BrdU) is a halogenated nucleotide of low toxicity commonly used to monitor DNA replication. It is considered a valuable tool for in vitro and in vivo studies, including the detection of the small population of neural stem cells (NSC) in the mammalian brain...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384327/ https://ncbi.nlm.nih.gov/pubmed/22379135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks207 |
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