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Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs
A novel class of small non-coding RNAs called DNA damage response RNAs (DDRNAs) generated at DNA double-strand breaks (DSBs) in a DROSHA- and DICER-dependent manner has been shown to regulate the DNA damage response (DDR). Similar molecules were also reported to guide DNA repair. Here, we show that...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478851/ https://ncbi.nlm.nih.gov/pubmed/31015566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42892-6 |
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