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Efficient Synthesis of Fmoc-Protected Phosphinic Pseudodipeptides: Building Blocks for the Synthesis of Matrix Metalloproteinase Inhibitors

A convenient route for the synthesis of Fmoc-protected phosphinic dipeptide building blocks is described. The protected amino acid isosteres benzyloxycarbonyl aminomethyl phosphinic acid (glycine surrogate), benzyl α-isopropyl acrylate (valine surrogate), and benzyl α-isobutyl acrylate (leucine surr...

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Bibliografiset tiedot
Päätekijät: Bhowmick, Manishabrata, Sappidi, Ravinder R., Fields, Gregg B., Lepore, Salvatore D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307803/
https://ncbi.nlm.nih.gov/pubmed/20225219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21425
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