Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome, and rhizomelic chondrodysplasia punctata

Many cell surface proteins in mammalian cells are anchored to the plasma membrane via glycosylphosphatidylinositol (GPI). The predominant form of mammalian GPI contains 1-alkyl-2-acyl phosphatidylinositol (PI), which is generated by lipid remodeling from diacyl PI. The conversion of diacyl PI to 1-a...

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Bibliografske podrobnosti
Main Authors: Kanzawa, Noriyuki, Shimozawa, Nobuyuki, Wanders, Ronald J. A., Ikeda, Kazutaka, Murakami, Yoshiko, Waterham, Hans R., Mukai, Satoru, Fujita, Morihisa, Maeda, Yusuke, Taguchi, Ryo, Fujiki, Yukio, Kinoshita, Taroh
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307642/
https://ncbi.nlm.nih.gov/pubmed/22253471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021204
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