Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome, and rhizomelic chondrodysplasia punctata

Many cell surface proteins in mammalian cells are anchored to the plasma membrane via glycosylphosphatidylinositol (GPI). The predominant form of mammalian GPI contains 1-alkyl-2-acyl phosphatidylinositol (PI), which is generated by lipid remodeling from diacyl PI. The conversion of diacyl PI to 1-a...

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Detalhes bibliográficos
Main Authors: Kanzawa, Noriyuki, Shimozawa, Nobuyuki, Wanders, Ronald J. A., Ikeda, Kazutaka, Murakami, Yoshiko, Waterham, Hans R., Mukai, Satoru, Fujita, Morihisa, Maeda, Yusuke, Taguchi, Ryo, Fujiki, Yukio, Kinoshita, Taroh
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307642/
https://ncbi.nlm.nih.gov/pubmed/22253471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021204
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