Heparanase Induces Signal Transducer and Activator of Transcription (STAT) Protein Phosphorylation: PRECLINICAL AND CLINICAL SIGNIFICANCE IN HEAD AND NECK CANCER

Activity of heparanase is implicated strongly in dissemination of metastatic tumor cells and cells of the immune system. In addition, heparanase enhances the phosphorylation of selected signaling molecules, including SRC and EGFR, in a manner that requires secretion but not enzymatic activity of hep...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cohen-Kaplan, Victoria, Jrbashyan, Jenny, Yanir, Yoav, Naroditsky, Inna, Ben-Izhak, Ofer, Ilan, Neta, Doweck, Ilana, Vlodavsky, Israel
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
Glycobiology and Extracellular Matrices
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307274/
https://ncbi.nlm.nih.gov/pubmed/22194600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.271346
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