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Heparanase augments EGF-receptor phosphorylation: correlation with head & neck tumor progression

Heparanase is an endoglycosidase that specifically cleaves heparan sulfate side chains, a class of glycosaminoglycans abundantly present in the extracellular matrix and on the cell surface. Heparanase activity is strongly implicated in tumor metastasis attributed to remodeling of the subepithelial a...

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Autori principali: Cohen-Kaplan, Victoria, Doweck, Ilana, Naroditsky, Inna, Vlodavsky, Israel, Ilan, Neta
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682916/
https://ncbi.nlm.nih.gov/pubmed/19074873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2910
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