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Heparanase induces VEGF C and facilitates tumor lymphangiogenesis
Heparanase is an endoglycosidase that specifically cleaves heparan sulfate side chains, a class of glycosaminoglycans abundantly present in the extracellular matrix and on the cell surface. Heparanase activity is strongly implicated in tumor angiogenesis and metastasis attributed to remodeling of th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575074/ https://ncbi.nlm.nih.gov/pubmed/18798279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23898 |
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