p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction

RATIONALE: Cardiomyocyte apoptosis is one of the key events in the development and progression of heart failure, and a crucial role for ICER (inducible cAMP early repressor) in this process has been previously reported. ERK5 is known to inhibit cardiac apoptosis after myocardial infarction (MI), esp...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Le, Nhat-Tu, Takei, Yuichiro, Shishido, Tetsuro, Woo, Chang-Hoon, Chang, Eugene, Heo, Kyung-Sun, Lee, Hakjoo, Lu, Yan, Morrell, Craig, Oikawa, Masayoshi, McClain, Carolyn, Wang, Xin, Tournier, Cathy, Molina, Carlos A., Taunton, Jack, Yan, Chen, Fujiwara, Keigi, Patterson, Cam, Yang, Jay, Abe, Jun-ichi
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306797/
https://ncbi.nlm.nih.gov/pubmed/22267842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.254730
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires