Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily

The rapid advance in genome sequencing presents substantial challenges for protein functional assignment, with half or more of new protein sequences inferred from these genomes having uncertain assignments. The assignment of enzyme function in functionally diverse superfamilies represents a particul...

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Detaylı Bibliyografya
Asıl Yazarlar: Lukk, Tiit, Sakai, Ayano, Kalyanaraman, Chakrapani, Brown, Shoshana D., Imker, Heidi J., Song, Ling, Fedorov, Alexander A., Fedorov, Elena V., Toro, Rafael, Hillerich, Brandan, Seidel, Ronald, Patskovsky, Yury, Vetting, Matthew W., Nair, Satish K., Babbitt, Patricia C., Almo, Steven C., Gerlt, John A., Jacobson, Matthew P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306705/
https://ncbi.nlm.nih.gov/pubmed/22392983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112081109
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