Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily

The rapid advance in genome sequencing presents substantial challenges for protein functional assignment, with half or more of new protein sequences inferred from these genomes having uncertain assignments. The assignment of enzyme function in functionally diverse superfamilies represents a particul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lukk, Tiit, Sakai, Ayano, Kalyanaraman, Chakrapani, Brown, Shoshana D., Imker, Heidi J., Song, Ling, Fedorov, Alexander A., Fedorov, Elena V., Toro, Rafael, Hillerich, Brandan, Seidel, Ronald, Patskovsky, Yury, Vetting, Matthew W., Nair, Satish K., Babbitt, Patricia C., Almo, Steven C., Gerlt, John A., Jacobson, Matthew P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306705/
https://ncbi.nlm.nih.gov/pubmed/22392983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112081109
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