Evolution of Enzymatic Activities in the Enolase Superfamily: Galactarate Dehydratase III from Agrobacterium tumefaciens C58

[Image: see text] The genome of Agrobacterium tumefaciens C58 encodes 12 members of the enolase superfamily (ENS), eight of which are members of the mandelate racemase (MR) subgroup and, therefore, likely to be acid sugar dehydratases. Using a library of 77 acid sugars for high-throughput screening,...

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Main Authors: Groninger-Poe, Fiona P., Bouvier, Jason T., Vetting, Matthew W., Kalyanaraman, Chakrapani, Kumar, Ritesh, Almo, Steven C., Jacobson, Matthew P., Gerlt, John A.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081050/
https://ncbi.nlm.nih.gov/pubmed/24926996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5005377
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