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Agonism/antagonism switching in allosteric ensembles
Ligands for several transcription factors can act as agonists under some conditions and antagonists under others. The structural and molecular bases of such effects are unknown. Previously, we demonstrated how the folding of intrinsically disordered (ID) protein sequences, in particular, and populat...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306695/ https://ncbi.nlm.nih.gov/pubmed/22388747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120519109 |
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