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Selective Small Molecule Inhibition of Poly(ADP-Ribose) Glycohydrolase (PARG)
The poly(ADP-ribose) (PAR) post-translational modification is essential for diverse cellular functions, including regulation of transcription, response to DNA damage, and mitosis. Cellular PAR is predominantly synthesized by the enzyme poly(ADP-ribose) polymerase-1 (PARP-1). PARP-1 is a critical nod...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306470/ https://ncbi.nlm.nih.gov/pubmed/22220926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200506t |
| Tagiau: |
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