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Synthesis of Dimeric ADP-Ribose and its Structure with Human Poly(ADP-Ribose) Glycohydrolase

Poly(ADP-ribosyl)ation is a common post-translational modification that mediates a wide variety of cellular processes including DNA damage repair, chromatin regulation, transcription, and apoptosis. The difficulty associated with accessing poly(ADP-ribose) (PAR) in a homogeneous form has been an imp...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lambrecht, Michael J., Brichacek, Matthew, Barkauskaite, Eva, Ariza, Antonio, Ahel, Ivan, Hergenrother, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089346/
https://ncbi.nlm.nih.gov/pubmed/25706250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja512528p
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