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The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
Posttranslational modification of proteins by poly(ADP-ribosyl)ation regulates many cellular pathways that are critical for genome stability, including DNA repair, chromatin structure, mitosis and apoptosis(1). Poly(ADP-ribose) (PAR) is composed of repeating ADP-ribose units linked via a unique glyc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184140/ https://ncbi.nlm.nih.gov/pubmed/21892188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10404 |
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