Heterodimerization of Glycosylated Insulin-Like Growth Factor-1 Receptors and Insulin Receptors in Cancer Cells Sensitive to Anti-IGF1R Antibody

BACKGROUND: Identification of predictive biomarkers is essential for the successful development of targeted therapy. Insulin-like growth factor 1 receptor (IGF1R) has been examined as a potential therapeutic target for various cancers. However, recent clinical trials showed that anti-IGF1R antibody...

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Main Authors: Kim, Jun Gyu, Kang, Min Jueng, Yoon, Young-Kwang, Kim, Hwang-Phill, Park, Jinah, Song, Sang-Hyun, Han, Sae-Won, Park, Jong-Wan, Kang, Gyeong Hoon, Kang, Keon Wook, Oh, Do Youn, Im, Seock-Ah, Bang, Yung-Jue, Yi, Eugene C., Kim, Tae-You
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306383/
https://ncbi.nlm.nih.gov/pubmed/22438913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033322
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