Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes

Insulin and IGF-1 actions in vascular smooth muscle cells (VSMC) are associated with accelerated arterial intima hyperplasia and restenosis after angioplasty, especially in diabetes. To distinguish their relative roles, we delete insulin receptor (SMIRKO) or IGF-1 receptor (SMIGF1RKO) in VSMC and in...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Nat Commun
Main Authors: Li, Qian, Fu, Jialin, Xia, Yu, Qi, Weier, Ishikado, Atsushi, Park, Kyoungmin, Yokomizo, Hisashi, Huang, Qian, Cai, Weikang, Rask-Madsen, Christian, Kahn, C. Ronald, King, George L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765023/
https://ncbi.nlm.nih.gov/pubmed/31562314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12368-2
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla