SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes

AIMS/HYPOTHESIS: Accelerated migration and proliferation of vascular smooth muscle cells (VSMCs) enhances arterial restenosis after angioplasty in insulin resistance and diabetes. Elevation of Src homology 2-containing protein tyrosine phosphatase 1 (SHP-1) induces apoptosis in the microvasculature....

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Gepubliceerd in:Diabetologia
Hoofdauteurs: Qi, Weier, Li, Qian, Liew, Chong Wee, Rask-Madsen, Christian, Lockhart, Samuel M., Rasmussen, Lars Melholt, Xia, Yu, Wang, Xuanchun, Khamaisi, Mogher, Croce, Kevin, King, George L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672905/
https://ncbi.nlm.nih.gov/pubmed/27933336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4159-1
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