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Integrity of mTORC2 is dependent on the rictor Gly-934 site
Growth factor signaling coupled to activation of the phosphatidylinositol-3-OH kinase (PI3K)/Akt pathway plays a crucial role in the regulation of cell proliferation and survival. The key regulatory kinase of Akt has been identified as mammalian target of rapamycin complex 2 (mTORC2), which function...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305845/ https://ncbi.nlm.nih.gov/pubmed/21909137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.404 |
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