Effects of the knockdown of hypoxia inducible factor-1α expression by adenovirus-mediated shRNA on angiogenesis and tumor growth in hepatocellular carcinoma cell lines

BACKGROUND/AIMS: Hypoxia-inducible factor-1α (HIF-1α) is a central transcriptional factor involved in the cellular responses related to various aspects of cancer biology, including proliferation, survival, and angiogenesis, and the metabolism of the extracellular matrix in hypoxia. This study evalua...

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Detalhes bibliográficos
Main Authors: Choi, Sung Hoon, Shin, Hye Won, Park, Jun Yong, Yoo, Ji Young, Kim, Do Young, Ro, Weon Sang, Yun, Chae-Ok, Han, Kwang-Hyub
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association for the Study of the Liver 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304594/
https://ncbi.nlm.nih.gov/pubmed/20924210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3350/kjhep.2010.16.3.280
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