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Repair of Chromosomal RAG-Mediated DNA Breaks by Mutant RAG Proteins Lacking PI-3-like Kinase Consensus Phosphorylation Sites

Ataxia telangiectasia mutated (ATM) and DNA-PKcs are members of the PI-3-like family of serine/threonine kinases that phosphorylate serines or threonines when positioned adjacent to a glutamine residue (SQ/TQ). Both kinases are activated rapidly by DNA double strand breaks (DSBs) and regulate the fu...

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Main Authors: Gapud, Eric J., Lee, Baeck-Seung, Mahowald, Grace K., Bassing, Craig H., Sleckman, Barry P.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304103/
https://ncbi.nlm.nih.gov/pubmed/21742970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101388
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