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Repair of Chromosomal RAG-Mediated DNA Breaks by Mutant RAG Proteins Lacking PI-3-like Kinase Consensus Phosphorylation Sites
Ataxia telangiectasia mutated (ATM) and DNA-PKcs are members of the PI-3-like family of serine/threonine kinases that phosphorylate serines or threonines when positioned adjacent to a glutamine residue (SQ/TQ). Both kinases are activated rapidly by DNA double strand breaks (DSBs) and regulate the fu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304103/ https://ncbi.nlm.nih.gov/pubmed/21742970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101388 |
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