A Novel Approach for the Rapid Mutagenesis and Directed Evolution of the Structural Genes of West Nile Virus

Molecular clone technology has proven to be a powerful tool for investigating the life cycle of flaviviruses, their interactions with the host, and vaccine development. Despite the demonstrated utility of existing molecular clone strategies, the feasibility of employing these existing approaches in...

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Huvudupphovsmän: Lin, Tsai-Yu, Dowd, Kimberly A., Manhart, Carolyn J., Nelson, Steevenson, Whitehead, Stephen S., Pierson, Theodore C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Genetic Diversity and Evolution
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302547/
https://ncbi.nlm.nih.gov/pubmed/22258236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06435-11
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