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A Novel Approach for the Rapid Mutagenesis and Directed Evolution of the Structural Genes of West Nile Virus

Molecular clone technology has proven to be a powerful tool for investigating the life cycle of flaviviruses, their interactions with the host, and vaccine development. Despite the demonstrated utility of existing molecular clone strategies, the feasibility of employing these existing approaches in...

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Detalhes bibliográficos
Main Authors: Lin, Tsai-Yu, Dowd, Kimberly A., Manhart, Carolyn J., Nelson, Steevenson, Whitehead, Stephen S., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302547/
https://ncbi.nlm.nih.gov/pubmed/22258236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06435-11
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