Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

Ítems similars

• Dolutegravir Resistance Mutation R263K Cannot Coexist in Combination with Many Classical Integrase Inhibitor Resistance Substitutions
  per: Anstett, Kaitlin, et al.
  Publicat: (2015)
• Combination of the R263K and M184I/V Resistance Substitutions against Dolutegravir and Lamivudine Decreases HIV Replicative Capacity
  per: Singhroy, Diane N., et al.
  Publicat: (2015)
• Effect of HIV-1 Integrase Resistance Mutations When Introduced into SIVmac239 on Susceptibility to Integrase Strand Transfer Inhibitors
  per: Hassounah, Said A., et al.
  Publicat: (2014)
• The R263K mutation in HIV integrase that is selected by dolutegravir may actually prevent clinically relevant resistance to this compound
  per: Wainberg, Mark, et al.
  Publicat: (2014)
• Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity
  per: Mesplède, Thibault, et al.
  Publicat: (2014)