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A role for insulator elements in the regulation of gene expression response to hypoxia

Hypoxia inducible factor (HIF) up-regulates the transcription of a few hundred genes required for the adaptation to hypoxia. This restricted set of targets is in sharp contrast with the widespread distribution of the HIF binding motif throughout the genome. Here, we investigated the transcriptional...

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Bibliografiska uppgifter
Huvudupphovsmän: Tiana, Maria, Villar, Diego, Pérez-Guijarro, Eva, Gómez-Maldonado, Laura, Moltó, Eduardo, Fernández-Miñán, Ana, Gómez-Skarmeta, Jose Luis, Montoliu, Lluís, del Peso, Luis
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300008/
https://ncbi.nlm.nih.gov/pubmed/22067454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr842
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