The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

Cells adapt to environmental changes, including fluctuations in oxygen levels, through the induction of specific gene expression programs. To identify genes regulated by hypoxia at the transcriptional level, we pulse-labeled HUVEC cells with 4-thiouridine and sequenced nascent transcripts. Then, we...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Tiana, Maria, Acosta-Iborra, Barbara, Puente-Santamaría, Laura, Hernansanz-Agustin, Pablo, Worsley-Hunt, Rebecca, Masson, Norma, García-Rio, Francisco, Mole, David, Ratcliffe, Peter, Wasserman, Wyeth W, Jimenez, Benilde, del Peso, Luis
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758878/
https://ncbi.nlm.nih.gov/pubmed/29059365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx951
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