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A role for insulator elements in the regulation of gene expression response to hypoxia
Hypoxia inducible factor (HIF) up-regulates the transcription of a few hundred genes required for the adaptation to hypoxia. This restricted set of targets is in sharp contrast with the widespread distribution of the HIF binding motif throughout the genome. Here, we investigated the transcriptional...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300008/ https://ncbi.nlm.nih.gov/pubmed/22067454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr842 |
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