LOW CSF Concentrations of the Nucleotide HIV Reverse Transcriptase Inhibitor, Tenofovir

Tenofovir is a nucleotide HIV reverse transcriptase inhibitor whose chemical properties suggest that it may not penetrate into the central nervous system in therapeutic concentrations. The study objective was to determine tenofovir penetration into cerebrospinal fluid (CSF). CHARTER is a multi-cente...

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Hlavní autoři: Best, Brookie M., Letendre, Scott L., Koopmans, Peter, Rossi, Steven S., Clifford, David B., Collier, Ann C., Gelman, Benjamin B., Marra, Christina M., McArthur, Justin C., McCutchan, J. Allen, Morgello, Susan, Simpson, David M., Capparelli, Edmund V., Ellis, Ronald J., Grant, Igor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299895/
https://ncbi.nlm.nih.gov/pubmed/22217676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318247ec54
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