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Local Gene Silencing of Monocyte Chemoattractant Protein-1 Prevents Vulnerable Plaque Disruption in Apolipoprotein E-Knockout Mice

Monocyte chemoattractant protein-1 (MCP-1), a CC chemokine (CCL2), has been demonstrated to play important roles in atherosclerosis and becoming an important therapeutic target for atherosclerosis. The present study was undertaken to test the hypothesis that local RNAi of MCP-1 by site-specific deli...

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Bibliografiske detaljer
Main Authors: Liu, Xiao Ling, Zhang, Peng Fei, Ding, Shi Fang, Wang, Yan, Zhang, Mei, Zhao, Yu Xia, Ni, Mei, Zhang, Yun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299803/
https://ncbi.nlm.nih.gov/pubmed/22428064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033497
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