Dominant-negative mutation of monocyte chemoattractant protein-1 prevents vulnerable plaques from rupture in rabbits independent of serum lipid levels

Active inflammation is an important feature of vulnerable plaques, and monocyte chemoattractant protein-1 (MCP-1) is a key chemokine that promotes monocyte–endothelium binding and initiates inflammation. We aimed to determine whether dominant-negative mutation of MCP-1 could reverse atherosclerotic...

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Pubblicato in:J Cell Mol Med
Autori principali: Zhong, Lin, Chen, Wen Qiang, Ji, Xiao Ping, Zhang, Mei, Zhao, Yu Xia, Yao, Gui Hua, Zhang, Peng Fei, Zhang, Cheng, Zhang, Yun
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2008
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514114/
https://ncbi.nlm.nih.gov/pubmed/18266972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00261.x
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