Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels

BACKGROUND AND PURPOSE: Atherosclerotic plaque rupture and thrombosis are the main cause of acute coronary syndrome. The study was aimed to test the hypothesis that oral administration of rapamycin may attenuate inflammation, inhibit progression and enhance stability of atherosclerotic plaques. EXPE...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Wen Qiang, Zhong, Lin, Zhang, Lei, Ji, Xiao Ping, Zhang, Mei, Zhao, Yu Xia, Zhang, Cheng, Zhang, Yun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2009
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697718/
https://ncbi.nlm.nih.gov/pubmed/19239473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00102.x
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