Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels

BACKGROUND AND PURPOSE: Atherosclerotic plaque rupture and thrombosis are the main cause of acute coronary syndrome. The study was aimed to test the hypothesis that oral administration of rapamycin may attenuate inflammation, inhibit progression and enhance stability of atherosclerotic plaques. EXPE...

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Detalhes bibliográficos
Main Authors: Chen, Wen Qiang, Zhong, Lin, Zhang, Lei, Ji, Xiao Ping, Zhang, Mei, Zhao, Yu Xia, Zhang, Cheng, Zhang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697718/
https://ncbi.nlm.nih.gov/pubmed/19239473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00102.x
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