Local Gene Silencing of Monocyte Chemoattractant Protein-1 Prevents Vulnerable Plaque Disruption in Apolipoprotein E-Knockout Mice

Monocyte chemoattractant protein-1 (MCP-1), a CC chemokine (CCL2), has been demonstrated to play important roles in atherosclerosis and becoming an important therapeutic target for atherosclerosis. The present study was undertaken to test the hypothesis that local RNAi of MCP-1 by site-specific deli...

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Detalhes bibliográficos
Main Authors: Liu, Xiao Ling, Zhang, Peng Fei, Ding, Shi Fang, Wang, Yan, Zhang, Mei, Zhao, Yu Xia, Ni, Mei, Zhang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299803/
https://ncbi.nlm.nih.gov/pubmed/22428064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033497
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