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Combinatorial interference of toll-like receptor 2 and 4 synergistically stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice

To test the hypothesis that combinatorial interference of toll-like receptor 2 (TLR2) and TLR4 is superior to isolated interference of TLR2 or TLR4 in stabilizing atherosclerotic plaques, lentiviruses carrying small interfering RNA of TLR2 or TLR4 were constructed and proved efficacious for knocking...

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Detalhes bibliográficos
Main Authors: Yang, Jian Min, Wang, Yan, Qi, Li Hang, Wang, Ying, Gao, Fei, Ding, Shi Fang, Ni, Mei, Liu, Chun Xi, Zhang, Cheng, Zhang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922382/
https://ncbi.nlm.nih.gov/pubmed/20132416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01028.x
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