Th17 cells and IL-17 are involved in the disruption of vulnerable plaques triggered by short-term combination stimulation in apolipoprotein E-knockout mice

Considerable evidence indicates that type 1 T helper (Th1)- and Th17-mediated immune responses promote the formation of atherosclerotic plaques while that CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) have a protective effect. However, the functions of diverse CD4(+) lymphocyte subsets in plaque...

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Detalhes bibliográficos
Main Authors: Ma, Tian, Gao, Qi, Zhu, Faliang, Guo, Chun, Wang, Qun, Gao, Fei, Zhang, Lining
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003212/
https://ncbi.nlm.nih.gov/pubmed/23542316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.4
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