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TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
Although aberrant microRNA (miRNA) expression is linked to human diseases including cancer, the mechanisms that regulate the expression of each individual miRNA remain largely unknown. TAR DNA-binding protein-43 (TDP-43) is homologous to the heterogeneous nuclear ribonucleoproteins (hnRNPs), which a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295278/ https://ncbi.nlm.nih.gov/pubmed/22323604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112427109 |
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